Acute organophosphate intoxication after using a anti-lice insecticide shampoo

Publication Type:Journal Article
Year of Publication:2002
Authors:C. Paget, Menard, S., Wroblewski, I., Gout, J. P., Danel, V., Bost, M.
Journal:Archives de Pediatrie
Pagination:913 - 916
Date Published:2002
ISBN Number:0929-693X
Keywords:abdomen, Acute Disease, animals, Antidotes/therapeutic use, child, Child, Preschool, English Abstract, hair, humans, insecticide, Lice Infestations/drug therapy, organophosphate, Pediculus, Portugal, scalp dermatoses, Time Factors, vomit

CASE REPORT: Two children were admitted for poisoning by organophosphate pesticides applied as hair rinses against lice. These chemical agents inhibit the acetylcholinesterase enzyme at various sites. The resultant accumulation of the transmitter acetylcholine causes abnormal signs and symptoms. The diagnosis is based on a reduction in the blood cholinesterase activity. The specific treatment comprises the administration of atropine and pralidoxime. CONCLUSION: Accidental poisoning by organophosphate insecticides may occur, due to the misuse of such substances as shampoo against lice. An accurate information for users is necessary.

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Scratchpads developed and conceived by (alphabetical): Ed Baker, Katherine Bouton Alice Heaton Dimitris Koureas, Laurence Livermore, Dave Roberts, Simon Rycroft, Ben Scott, Vince Smith