A century of typhus, lice and Rickettsia

Publication Type:Journal Article
Year of Publication:2000
Authors:J. O. Andersson, Andersson S. G.
Journal:Research in Microbiology
Pagination:143 - 150
Date Published:2000
ISBN Number:0923-2508
Keywords:animals, France, genome, history, humans, Lice/microbiology, Mitochondria/genetics, phylogeny, Rickettsia prowazekii/genetics, sequence, typhus

At the beginning of the 20th century, it was discovered at the Pasteur Institute in Tunis that epidemic typhus is transmitted by the human body louse. The complete genome sequence of its causative agent, Rickettsia prowazekii, was determined at Uppsala University in Sweden at the end of the century. In this mini-review, we discuss insights gained from the genome sequence of this fascinating and deadly organism.

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