|Publication Type:||Journal Article|
|Year of Publication:||2000|
|Authors:||C. G. Burkhart, Burkhart C. N.|
|Journal:||Journal of Cutaneous Medicine and Surgery|
|Pagination:||199 - 201|
|Keywords:||animals, child, Drug Combinations, Drug Resistance, Microbial, humans, insecticide, Lice Infestations/drug therapy, Pediculus, Permethrin, Piperonyl Butoxide, Pyrethrum, scalp dermatoses, Treatment Failure|
BACKGROUND: Over-the-counter insecticidal solutions continue to be the mainstream treatment for most cases of head lice. Recorded insecticidal activity 15 years ago was at 100%, with ovicidal kill at 80%. Recently scattered accounts of possible resistance have surfaced. OBJECTIVE: This article is to document the general consensus that head lice are becoming resistant to standard over-the-counter therapies. METHODS: Direct testing of lethality of adult lice with permethrin and pyrethroid was assessed. RESULTS: Present over-the-counter products proved to be successful in only 9 of 32 head lice tested (28% insecticidal activity). CONCLUSIONS: Our series of cases further documents that over-the-counter head lice preparations no longer achieve high levels of insecticidal activity, suggesting increased resistance to these insecticides.
Clinical evidence of lice resistance to over-the-counter products