|Publication Type:||Journal Article|
|Year of Publication:||1996|
|Authors:||F. E. Phillips, Logan, N. B., Jones, R. M.|
|Journal:||American Journal of Veterinary Research|
|Pagination:||1468 - 1471|
|Keywords:||animals, anthelmintic, cattle, Cattle Diseases, gastrointestinal, Haemonchus, Injections, insecticide, Ivermectin/administration & dosage/analogs & derivatives/therapeutic use, lice, Lice Infestations/drug therapy/veterinary, Nematoda/isolation & purification, Nematode Infections/drug therapy/veterinary, Ostertagia/isolation & purification, Trichostrongylus|
OBJECTIVE: To evaluate the safety and efficacy of doramectin given by injection at a dosage of 200 micrograms/kg of body weight for treatment of gastrointestinal nematodiasis or louse infestations of cattle.ANIMALS: 1,031 mixed-breed cattle were treated in the nematode study and 418 were treated in the louse study. PROCEDURE: Naturally parasitized cattle were given 200 micrograms of doramectin/kg or an equivalent volume of saline solution, SC. In nematode experiments, fecal samples were collected from each animal 1 week before treatment, at time of treatment, and at weekly intervals there after for 3 weeks. In louse experiments, louse counts were carried out for each animal on the day of treatment and 14 and 28 days later. All cattle were weighted at the time of treatment and at the end of the experiment.