Spectrum of activity of doramectin against cattle mites and lice

Publication Type:Journal Article
Year of Publication:1993
Authors:N. B. Logan, Weatherley, A. J., Phillips, F. E., Wilkins, C. P., Shanks, D. J.
Journal:Veterinary parasitology
Pagination:67 - 73
Date Published:1993
ISBN Number:0304-4017
Keywords:animals, Anoplura, cattle, Cattle Diseases, Injections, insecticide, Ivermectin/administration & dosage/analogs & derivatives/therapeutic use, Lice Infestations/drug therapy/veterinary, Mallophaga, Mite Infestations/drug therapy/veterinary, scabies

A series of 16 studies was conducted involving 288 cattle with naturally acquired or experimentally induced mite or louse infestations to evaluate the efficacy of doramectin. Four studies were conducted against the mite species Psoroptes bovis and two against the mite species Sarcoptes scabiei. Ten studies involved cattle with one or more of the following louse species: Damalinia bovis, Haematopinus eurysternus, Linognathus vituli and Solenopotes capillatus. In each study, a group of at least nine but not more than 25 cattle were randomly allocated to a control or a treated group. One group was treated with doramectin at 200 micrograms kg-1 and the other group received no medication. Mites or lice were quantified by species immediately before treatment and at weekly intervals for 4 weeks thereafter. Doramectin was 100% efficacious against infestations of P. bovis, Sarcoptes scabiei, H. eurysternus, L. vituli and Solenopotes capillatus. The drug reduced infestations of D. bovis by a mean of 82%.

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