Survey of three bacterial louse-associated diseases among rural Andean communities in Peru: prevalence of epidemic typhus, trench fever, and relapsing fever

Publication Type:Journal Article
Year of Publication:1999
Authors:D. Raoult, Birtles, R. J., Montoya, M., Pérez, E., Tissot-Dupont, H., Roux, V., Guerra, H.
Journal:Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume:29
Issue:2
Pagination:434 - 436
Date Published:1999
ISBN Number:1058-4838
Keywords:adult, animals, Antibodies, Bacterial/blood, Borrelia, humans, Insect vectors, Lice/microbiology, Peru, populations, prevalence, Relapsing Fever, trench fever, typhus
Abstract:

Typhus and other louse-transmitted bacterial infections in Peruvian sierra communities are known to occur but have not recently been assessed. In this study, 194 of 1,280 inhabitants of four villages in Calca Province in the Urubamba Valley were included. Thirty-nine (20%) of the 194 volunteers had antibodies to Rickettsia prowazekii, whereas 24 (12%) had antibodies to Bartonella quintana and 2 against Borrelia recurrentis. There was a significant correlation between the presence of infesting ectoparasites and antibodies to R. prowazekii, as well as between antibodies to R. prowazekii and ectoparasite infestation and fever in the previous 6 months. The proportion of inhabitants infested with ectoparasites was significantly higher in the highest-altitude village than in the other three villages. Two volunteers' antibody levels suggested a recent typhus infection, but only B. quintana DNA was amplified from lice. Epidemic typhus remains extant in the area, and B. quintana infections were encountered and documented for the first time in South America.

URL:https://academic.oup.com/cid/article/29/2/434/274388
DOI:10.1086/520229
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