|Publication Type:||Journal Article|
|Year of Publication:||2011|
|Authors:||K. Sup Yoon, Strycharz, J. P., Baek, J. H., Sun, W., Kim, J. H., Kang, J. S., Pittendrigh, B. R., Lee, S. Hyeock, J. Clark, M.|
|Journal:||Insect Molecular Biology|
|Pagination:||687 - 699|
|Date Published:||Sept 2011|
Transcriptional profiling results, using our non-invasive induction assay [short exposure intervals (2–5 h) to sub-lethal amounts of insecticides (<LD3 at 24 h) administered by stress reducing means (contact vs. immersion screen) and with induction assessed in a time frame when tolerance is still present (~LC90 in 2–4 h)], show that ivermectin-induced detoxification genes from body lice are identified by quantitative real-time PCR analyses.
Brief exposures of human body lice to sublethal amounts of ivermectin over-transcribes detoxification genes involved in tolerance